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Evidence collected at crime scenes—everything from fingerprints to bite marks—is routinely called upon in the courtroom to prosecute the most difficult crimes and put the guilty behind bars. And though glamorized on commercial television, in the real world, it's not so cut-and-dried. A joint investigation by FRONTLINE, ProPublica and the Investigative Reporting Program at UC Berkeley examines the reliability of the science behind forensics in The Real CSI. From the sensational murder trial of Casey Anthony to the credentialing of forensic experts, “The Real CSI” documents how a field with few uniform standards and unproven science can undermine the search for justice. The investigation follows a landmark study by the National Academy of Sciences that called into question the tenets of forensic science. For the first time, Harry T. Edwards, a senior federal appellate court judge and co-chairman of the report, sits for an interview to discuss what the report means. And, FRONTLINE examines one of the most high-profile terrorist investigations since 9/11: the case of Brandon Mayfield, an attorney who was wrongfully identified and arrested as a suspect in the Madrid commuter train bombings after the FBI erroneously matched his fingerprint to a partial print found at the scene. In “The Real CSI,” FRONTLINE correspondent Lowell Bergman finds serious flaws in some of the best known tools of forensic science, wide inconsistencies in how forensic evidence is presented in the courtroom and no system in place for establishing the credibility of so-called “forensic experts” whose testimony can lead to a conviction.